25-11-2022, 16:49 | view 👀:8 | 🙍 oneddl | redaktor: book24h | Rating👍:

Retrotransposons and Human Disease L1 Retrotransposons as a Source of Genetic Diversity [#490589]

Name: Retrotransposons and Human Disease L1 Retrotransposons as a Source of Genetic Diversity
Author: book24h

Retrotransposons And Human Disease: L1 Retrotransposons As A Source Of Genetic Diversity
by Abram Gabriel;
English | 2022 | ISBN: 9811249210 | 260 pages | True PDF EPUB | 25.83 MB
Thirty years ago we knew that retrotransposons made up at least half of our genomes, but little about their role in biology. The human genome has since been sequenced and the position of all retrotransposons in the reference sequence has been determined. However, as of today, the function of retrotransposons still remains elusive. We know much more about the diseases associated with their movement and the host defenses we all have against them.

This volume explores an array of diseases in humans associated with L1 retrotransposon movement within the human genome, including some cancers such as colon cancer and neuropsychiatric disorders such as schizophrenia.
The chapters explore the diversity of retrotransposons, their different biological mechanisms, the role of L1 in their movement, and their contribution to human diseases. This book posits that somatic events caused by retrotransposons have implications for mosaicism and are often associated with cancers. Germline events are common, occur quite early in development, and are a cause of single gene diseases. All in all, the authors implicate L1 retrotransposons as major sources of human diversity and advocate for their continued study.
Contents:PrefaceThe Diversity of Reverse Transcriptases (Blair G Paul, Irina A Yushenova, and Irina R Arkhipova)Ty3 and Related LTR-Retrotransposon Reverse Transcriptases (Jennifer T Miller and Stuart F J Le Grice)Experimental Systems for the Study of Non-LTR (LINE) Retrotransposons (Ivana Celic and Jeffrey S Han)Alu Elements and Human Disease (Hanlin Yang, Maria E Morales, and Astrid M Roy-Engel)Retrotransposition as a Cause of Human Disease: An Update (Haig H Kazazian)LINE-1 Retrotransposons, Stem Cells, and Human Neurodevelopmental Disorders (Maria Benitez-Guijarro, Meriem Benkaddour-Boumzaouad, and Jose L Garcia-Perez)Retrotransposition Mechanisms and Host Factors (Siew Loon Ooi, Kathleen H Burns, and Jef D Boeke)Retrotransposons in the Mammalian Brain (Tracy A Bedrosian, Sara B Linker, and Fred H Gage)LINE-1 Mobilization in Cancers: More the Rule than the Exception (Daniel Ardeljan and Kathleen H Burns)Index
Readership: Researchers from both academia and industry, graduate students, premed students, clinicians.

Download From 1DL
.html
rapidgator

https://rapidgator.net/file/f2a05561ccbbaa4a0c8b06b097ff9555/oc9c2.R.a.H.D.L.R.a.a.S.o.G.D.rar.html

Please Help Me Click Connect Icon Below Here and Share News to Social Network | Thanks you !

⚠️ Dead Link ?
You may submit a re-upload request using the search feature. All requests are reviewed in accordance with our Content Policy.

Request Re-upload

Significant surge in the popularity of free ebook download platforms. These virtual repositories offer an unparalleled range, covering genres that span from classic literature to contemporary non-fiction, and everything in between. Enthusiasts of reading can easily indulge in their passion by accessing free books download online services, which provide instant access to a wealth of knowledge and stories without the physical constraints of space or the financial burden of purchasing hardcover editions.

Retrotransposons and Human Disease L1 Retrotransposons as a Source of Genetic Diversity [#490589]

Comments (0)

Log in